SCHEMBL7731451

SCHEMBL7731451

COC(C)OP(N)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoramidic Acid SCHEMBL220946 0.98 LAP3 (0.32)
SCHEMBL2524893 0.79 CA2 (0.33)
SCHEMBL1514201 0.79
SCHEMBL3693476 0.79 CTSA (0.32)
SCHEMBL8399409 0.76
Phosphoric Acid SCHEMBL26662213 0.75 CA2 (0.38)
Ammonia Solution, Strong SCHEMBL27820268 0.74
SCHEMBL2048661 0.73 CTSA (0.35)
SCHEMBL8724557 0.71
SCHEMBL4951275 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12458705-B2 Antibody-oligonucleotide conjugates ANGIEX, INC. (US) 2025-11-04 US disclosed
EP-4475891-A2 ENHANCED DNA DENDRIMERS AND METHODS OF USE THEREOF Code Biotherapeutics, Inc. (US) 2024-12-18 EP disclosed
US-20230338557-A1 ENHANCED DNA DENDRIMERS AND METHODS OF USE THEREOF CODE BIOTHERAPEUTICS, INC. 2023-10-26 US disclosed
WO-2023154788-A2 ENHANCED DNA DENDRIMERS AND METHODS OF USE THEREOF CODE BIOTHERAPEUTICS, INC. (US) 2023-08-17 WO disclosed
US-20230015276-A1 METHODS AND COMPOSITIONS TO INCREASE SOMATIC CELL NUCLEAR TRANSFER (SCNT) EFFICIENCY BY REMOVING HISTONE H3-LYSINE TRIMETHYLATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-01-19 US disclosed
US-20220265770-A1 TREATING NEURODEGENERATIVE DISEASES WITH PROGRANULIN NEURODYN INC (CA) 2022-08-25 US disclosed
US-20220242964-A1 COMPOSITIONS AND METHODS FOR REGULATING ERYTHROPOIESIS UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2022-08-04 US disclosed
US-11390885-B2 Methods and compositions to increase somatic cell nuclear transfer (SCNT) efficiency by removing histone H3-lysine trimethylation CHILDREN'S MEDICAL CENTER CORPORATION (US) 2022-07-19 US disclosed
CN-112912110-A Antibody-oligonucleotide conjugates 安吉克公司 2021-06-04 CN disclosed
CN-112135907-A Peptide nucleic acid complexes with inclusion body escape capability and uses thereof 海阳制药股份有限公司 2020-12-25 CN disclosed
US-5734040-A OLIGONUCLEOTIDES WITH ETHYLENEDIAMINE PHOSPHORAMIDATE FOR DNA UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1998-03-31 US disclosed
WO-1998003533-A1 ANTISENSE OLIGONUCLEOTIDES AS ANTIBACTERIAL AGENTS OLIGOS ETC. AND OLIGOS THERAPEUTICS, INC. (US) 1998-01-29 WO disclosed
EP-0498843-B1 OLIGONUCLEOTIDE ANALOGS WITH NOVEL LINKAGES GILEAD SCIENCES INC (US) 1996-06-12 EP disclosed
US-5495009-A TREATING WITH BROMINE IN PRESENCE OF 2,6-DIETHYLPYRIDINE AND MOLECULAR SIEVES FOLLOWED BY TREATMENT WITH TETRABUTYLAMMONIUM FLUORIDE IN TETRAHYDROFURAN GILEAD SCIENCES, INC. (US) 1996-02-27 US disclosed
US-5264564-A DNA or RNA and gene expression GILEAD SCIENCES (US) 1993-11-23 US disclosed
US-5264562-A Replacement of phosphodiester linkages with some acetal/ketal type, resistant to nuclease digestion GILEAD SCIENCES, INC. (US) 1993-11-23 US disclosed
WO-1992019637-A1 OLIGONUCLEOTIDE ANALOGS CONTAINING THIOFORMACETAL LINKAGES GILEAD SCIENCES, INC. (US) 1992-11-12 WO disclosed
EP-0498843-A4 OLIGONUCLEOTIDE ANALOGS WITH NOVEL LINKAGES 1992-11-04 EP disclosed
EP-0498843-A1 OLIGONUCLEOTIDE ANALOGS WITH NOVEL LINKAGES. GILEAD SCIENCES INC (US) 1992-08-19 EP disclosed
WO-1991006629-A1 OLIGONUCLEOTIDE ANALOGS WITH NOVEL LINKAGES GILEAD SCIENCES, INC. (US) 1991-05-16 WO disclosed