Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205258 | 0.88 | L3MBTL1 (0.75) | L3MBTL1MAPTMAOBGAAHTT | |
| SCHEMBL29270738 | 0.82 | L3MBTL1 (0.66) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL18381590 | 0.81 | MAPT (0.70) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL29270743 | 0.80 | L3MBTL1 (0.59) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL26962714 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL15346534 | 0.79 | HTT (0.79) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL9340146 | 0.79 | HTT (0.79) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL9874334 | 0.79 | HTT (0.79) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL20500014 | 0.78 | L3MBTL1 (0.74) | L3MBTL1MAPTTGM2HTTLMNA | |
| SCHEMBL20497343 | 0.78 | L3MBTL1 (0.63) | L3MBTL1MAPTTGM2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |