Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500014 | 0.90 | L3MBTL1 (0.74) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL7732296 | 0.88 | L3MBTL1 (0.60) | L3MBTL1MAPTMAOBSMN1; SMN2LMNA | |
| SCHEMBL9272300 | 0.88 | L3MBTL1 (0.81) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL3811564 | 0.88 | L3MBTL1 (0.80) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6331080 | 0.87 | L3MBTL1 (0.71) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL20008740 | 0.87 | L3MBTL1 (0.71) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL24627827 | 0.86 | L3MBTL1 (0.70) | L3MBTL1MAPTMAOBSMN1; SMN2LMNA | |
| SCHEMBL28677911 | 0.86 | MAPT (0.78) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL4839180 | 0.84 | MAPT (0.71) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL20299180 | 0.84 | L3MBTL1 (0.79) | L3MBTL1MAPTSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389437-B1 | Luciferin derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5128069-A | Luciferin derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0389437-A1 | Luciferin derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |