Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466167 | 0.85 | CES1 (0.46) | CES1ANPEPERAP1ERAP2HDAC1 | |
| SCHEMBL7732052 | 0.79 | RAB9A (0.43) | HDAC1HDAC8HDAC6KMT2AMETAP2 | |
| SCHEMBL7732103 | 0.76 | RAB9A (0.53) | HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL7735836 | 0.76 | SLC1A3 (0.40) | KMT2AMETAP2 | |
| SCHEMBL6463614 | 0.76 | HDAC1 (0.45) | CES1HDAC1HDAC8HDAC6FAAH | |
| SCHEMBL5168702 | 0.75 | HDAC1 (0.43) | CES1HDAC1HDAC8HDAC6PTPN1 | |
| SCHEMBL7723269 | 0.73 | MAPT (0.48) | KMT2A | |
| SCHEMBL6463446 | 0.73 | DAGLA (0.51) | CES1ERAP2HDAC1HDAC8HDAC6 | |
| SCHEMBL25387512 | 0.71 | HDAC1 (0.40) | CES1HDAC1HDAC8HDAC6PTPN1 | |
| SCHEMBL2078861 | 0.70 | HDAC1 (0.54) | CES1HDAC1HDAC8HDAC6PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |