Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733597 | 0.80 | MAPT (0.51) | CASP1MAPTCTSLCTSBCTSS | |
| Trifluoroacetic Acid SCHEMBL7732364 | 0.78 | PRSS1 (0.40) | CASP1MAPTPRSS1PRSS2PRSS3 | |
| SCHEMBL15867717 | 0.78 | TDP1 (0.46) | MAPTTSHRSLC6A2SLC6A3KMT2A | |
| SCHEMBL7732052 | 0.76 | RAB9A (0.43) | MAPTCYP1A2METAP2KMT2ATDP1 | |
| SCHEMBL7732335 | 0.76 | CES1 (0.49) | METAP2KMT2A | |
| SCHEMBL7733653 | 0.75 | MAPT (0.40) | MAPTTPSAB1CTSBCTSSKMT2A | |
| SCHEMBL7736280 | 0.72 | DAGLA (0.34) | METAP2CTSBCTSSKMT2AALDH1A1 | |
| SCHEMBL7734004 | 0.71 | RAB9A (0.42) | MAPTKMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL800520 | 0.70 | DAGLA (0.47) | SLC1A1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6193806 | 0.69 | LMNA (0.44) | MAPTTSHREGLN1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |