SCHEMBL7732348

SCHEMBL7732348

B.Fc1ccccc1-c1ccccc1.Fc1ccccc1-c1ccccc1.Fc1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
MAPK1 P28482 2/20 0.48
RAB9A P51151 2/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
PKM P14618 1/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
KMT2A Q03164 1/20 0.48
RELA Q04206 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 5/20 0.47
MAPT P10636 1/20 0.47
PTPRC P08575 1/20 0.47
PTPN1 P18031 1/20 0.47
HSD17B10 Q99714 2/20 0.46
HPGD P15428 1/20 0.46
BCL2L1 Q07817 1/20 0.46
CYP2A6 P11509 1/20 0.46
ACMSD Q8TDX5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201614 0.97 L3MBTL1 (0.50) L3MBTL1MAPK1RAB9AMEN1NPC1
SCHEMBL28005840 0.94 L3MBTL1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
SCHEMBL29208960 0.94 L3MBTL1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
Methane SCHEMBL27570582 0.94 L3MBTL1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
Hydrochloric Acid SCHEMBL29097687 0.94 MAPK1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
Bromide SCHEMBL29097483 0.94 L3MBTL1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
SCHEMBL29220725 0.94 L3MBTL1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
SCHEMBL27649165 0.94 L3MBTL1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
Lithium SCHEMBL30864202 0.94 L3MBTL1 (0.48) L3MBTL1MAPK1RAB9AMEN1NPC1
SCHEMBL2140802 0.92 ALDH1A1 (0.50) L3MBTL1MAPK1RAB9AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403732-B2 COORDIATION CATALSYTS OF ORGANOBORANES AND METALLOCENES FOR ADDITION POLYMERIZATION NORTHWESTERN UNIVERSITY 2002-06-11 US disclosed
US-20010034424-A1 Organo-lewis acids of enhanced utility, uses thereof, and products based thereon ENERGY, UNITED STATES DEPARTMENT OF 2001-10-25 US disclosed
US-6291695-B1 AS COCATALYSTS IN USED IN POYMERIZATION REACTIONS NORTHWESTERN UNIVERSITY 2001-09-18 US disclosed