SCHEMBL7732408

SCHEMBL7732408

CCO[Si](OCC)(OCC)c1cccc(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
MAPK1 P28482 2/20 0.41
IDO1 P14902 2/20 0.41
HTR2A P28223 2/20 0.40
HTR2B P41595 2/20 0.40
HTR2C P28335 1/20 0.40
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PNMT P11086 1/20 0.39
MAPT P10636 3/20 0.39
SIGMAR1 Q99720 1/20 0.39
LMNA P02545 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
DRD3 P35462 1/20 0.39
OPRK1 P41145 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15733442 0.92 L3MBTL1 (0.40) L3MBTL1MAPK1IDO1HTR2AHTR2B
SCHEMBL15736663 0.92 L3MBTL1 (0.40) L3MBTL1MAPK1IDO1HTR2AHTR2B
SCHEMBL7731149 0.87 L3MBTL1 (0.41) L3MBTL1MAPK1IDO1HTR2AHTR2B
SCHEMBL23521414 0.86 IDO1 (0.45) L3MBTL1MAPK1IDO1HTR2AHTR2B
SCHEMBL15736496 0.85 L3MBTL1 (0.42) L3MBTL1MAPK1IDO1HTR2AHTR2B
SCHEMBL15750752 0.85 L3MBTL1 (0.42) L3MBTL1MAPK1IDO1HTR2AHTR2B
SCHEMBL15733957 0.84 MAOB (0.49) L3MBTL1IDO1NPSR1MAPTALDH1A1
SCHEMBL23040287 0.84 NR1H3 (0.46) LMNA
SCHEMBL15735872 0.83 L3MBTL1 (0.41) L3MBTL1MAPK1IDO1HTR2AHTR2B
SCHEMBL26532196 0.83 CYP4F2 (0.38) MAPK1TSHRTAS1R3TAS1R1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
US-20170218128-A1 Curable Silicone Resin Composition, Cured Object Obtained Therefrom, and Optical Semiconductor Device Formed Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-08-03 US disclosed
CN-106574118-A Curable silicone resin composition, cured product thereof, and optical semiconductor device using same 中央硝子株式会社 2017-04-19 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed
US-6399733-B1 SILICONES MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-06-04 US disclosed