Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217375 | 0.75 | NPSR1 (0.51) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL7731390 | 0.74 | NPSR1 (0.44) | NPSR1TDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7735993 | 0.74 | NPSR1 (0.46) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL7732543 | 0.73 | TDP1 (0.46) | NPSR1TDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7775267 | 0.73 | ALDH1A1 (0.46) | NPSR1TDP1TSHRALDH1A1GPR35 | |
| SCHEMBL3126302 | 0.69 | GPR35 (0.65) | TDP1TSHRL3MBTL1ALDH1A1GPR35 | |
| Selenium SCHEMBL11463644 | 0.67 | GPR35 (0.62) | TDP1TSHRL3MBTL1ALDH1A1GPR35 | |
| SCHEMBL7731241 | 0.67 | TDP1 (0.42) | NPSR1TDP1TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL22090177 | 0.66 | NPSR1 (0.60) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL12003841 | 0.66 | NPSR1 (0.51) | NPSR1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407083-B1 | ADMINISTERING AS 7-NITROBENZISOSELENAZOLINE DERIVATIVES AS ANTITUMOR AND ANTICARCINOGENIC AGENTS | OXIS INTERNATIONAL, INC. | 2002-06-18 | — | — | US | disclosed |
| US-6130212-A | ANTITUMOR | OXIS INTERNATIONAL S.A. (US) | 2000-10-10 | — | — | US | disclosed |
| US-6057310-A | TREATING LEUKEMIA, BREAST CANCER | OXIS ISLE OF MAN, LIMITED (US) | 2000-05-02 | — | — | US | disclosed |
| US-6001825-A | Use of novel organoselenium compounds as pro-oxidizing agents their methods of preparation and pharmaceutical compositions and application thereof | OXIS ISLE OF MAN, LIMITED (US) | 1999-12-14 | — | — | US | disclosed |
| EP-0819682-A1 | Use of novel organoselenium compounds as pro-oxidizing agents, their methods of preparation and pharmaceutical compositions and application containing them | Oxis International S.A. (FR) | 1998-01-21 | — | — | EP | disclosed |