Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730819 | 0.96 | THRB (0.33) | DAOPPARGPPARAS1PR1PDE2A | |
| SCHEMBL7731647 | 0.93 | S1PR1 (0.31) | PSEN1S1PR1S1PR3HDAC3HDAC1 | |
| SCHEMBL7730397 | 0.93 | DAO (0.33) | DAOPPARGPPARA | |
| SCHEMBL7730657 | 0.93 | PSEN1 (0.37) | PSEN1PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL7734945 | 0.91 | PSEN1 (0.36) | DAOPSEN1PPARGPPARAS1PR1 | |
| SCHEMBL7730235 | 0.91 | S1PR1 (0.36) | PSEN1PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL7730038 | 0.91 | DAO (0.37) | DAOS1PR1S1PR3 | |
| SCHEMBL7729444 | 0.90 | PSEN1 (0.36) | PSEN1PPARGS1PR1S1PR3 | |
| SCHEMBL7732500 | 0.90 | HDAC3 (0.33) | PPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL14226647 | 0.89 | RARB (0.38) | PSEN1PPARGPPARAS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |