Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730440 | 0.96 | THRB (0.39) | PPARGPPARADAOS1PR1THRB | |
| SCHEMBL7730657 | 0.94 | PSEN1 (0.37) | PSEN1PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL7732213 | 0.92 | DAO (0.36) | PPARGPPARADAOMAOBTHRB | |
| SCHEMBL7730235 | 0.92 | S1PR1 (0.36) | PSEN1PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL7735067 | 0.92 | DAO (0.36) | PSEN1PPARGPPARADAOS1PR1 | |
| SCHEMBL7732755 | 0.91 | DAO (0.32) | PSEN1PPARGPPARADAOS1PR1 | |
| SCHEMBL7730677 | 0.91 | RARB (0.41) | PSEN1PPARGPPARAS1PR1MAOB | |
| SCHEMBL7729444 | 0.91 | PSEN1 (0.36) | PSEN1PPARGS1PR1S1PR3MAOB | |
| SCHEMBL14226647 | 0.90 | RARB (0.38) | PSEN1PPARGPPARAS1PR1S1PR3 | |
| SCHEMBL7733324 | 0.90 | S1PR1 (0.35) | PSEN1PPARGPPARAS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |