Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731366 | 0.97 | FAAH (0.39) | CA2CA1FAAHPLK1ALDH1A1 | |
| SCHEMBL7731911 | 0.97 | FAAH (0.45) | FAAHALDH1A1THRBHSD17B10SMN1; SMN2 | |
| SCHEMBL7729811 | 0.95 | FAAH (0.41) | CA2CA1FAAHPLK1ALDH1A1 | |
| SCHEMBL7722878 | 0.95 | PSEN1 (0.43) | PPARAPSEN1HDAC1MEN1KMT2A | |
| SCHEMBL7722561 | 0.95 | FAAH (0.48) | FAAHALDH1A1THRBHSD17B10SMN1; SMN2 | |
| SCHEMBL7722899 | 0.95 | PSEN1 (0.43) | PPARAPSEN1HDAC1MEN1KMT2A | |
| SCHEMBL7731048 | 0.95 | FAAH (0.48) | FAAHALDH1A1THRBHSD17B10SMN1; SMN2 | |
| SCHEMBL7733465 | 0.95 | FAAH (0.48) | FAAHALDH1A1THRBHSD17B10SMN1; SMN2 | |
| SCHEMBL7735066 | 0.95 | FAAH (0.48) | FAAHALDH1A1THRBHSD17B10SMN1; SMN2 | |
| SCHEMBL7732506 | 0.95 | HDAC3 (0.45) | CA2CA1FAAHPLK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |