Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722878 | 1.00 | PSEN1 (0.43) | PSEN1MAOBTAAR1MEN1KMT2A | |
| SCHEMBL7730087 | 0.98 | PSEN1 (0.43) | PSEN1MAOBTAAR1MEN1KMT2A | |
| SCHEMBL7729408 | 0.95 | FAAH (0.43) | PSEN1MAOBTAAR1MEN1KMT2A | |
| SCHEMBL7733443 | 0.95 | FAAH (0.43) | PSEN1MAOBTAAR1MEN1KMT2A | |
| SCHEMBL7732798 | 0.95 | CA2 (0.41) | PSEN1MEN1KMT2APPARAHDAC1 | |
| SCHEMBL7730131 | 0.94 | FAAH (0.42) | PSEN1MAOBTAAR1MEN1KMT2A | |
| SCHEMBL7731911 | 0.92 | FAAH (0.45) | MEN1KMT2A | |
| SCHEMBL7731366 | 0.92 | FAAH (0.39) | PSEN1MEN1KMT2APPARAHDAC1 | |
| SCHEMBL7733465 | 0.91 | FAAH (0.48) | MEN1KMT2A | |
| SCHEMBL7729811 | 0.91 | FAAH (0.41) | PSEN1MEN1KMT2APPARAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |