Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182044 | 0.80 | NR1H2 (0.35) | NR1H2 | |
| SCHEMBL3310033 | 0.79 | NR1H2 (0.34) | NR1H2MEN1KMT2A | |
| SCHEMBL76722 | 0.79 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL23942085 | 0.79 | NR1H2 (0.36) | NR1H2SMN1; SMN2 | |
| SCHEMBL2146337 | 0.79 | NR1H2 (0.36) | NR1H2SMN1; SMN2 | |
| SCHEMBL18321103 | 0.79 | NR1H2 (0.36) | NR1H2SMN1; SMN2 | |
| SCHEMBL27223224 | 0.76 | ABCB1 (0.41) | PRMT5WDR77MEN1KMT2A | |
| SCHEMBL704571 | 0.76 | ABCB1 (0.41) | PRMT5WDR77MEN1KMT2A | |
| SCHEMBL23043429 | 0.76 | ABCB1 (0.41) | PRMT5WDR77MEN1KMT2A | |
| SCHEMBL15091703 | 0.76 | NR1H2 (0.52) | NR1H2MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129373-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |