Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182044 | 0.81 | NR1H2 (0.35) | NR1H2 | |
| SCHEMBL76722 | 0.81 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL23942085 | 0.80 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL2146337 | 0.80 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL18321103 | 0.80 | NR1H2 (0.36) | NR1H2 | |
| SCHEMBL77330 | 0.79 | PRMT5 (0.39) | NR1H2MEN1KMT2A | |
| SCHEMBL704571 | 0.78 | ABCB1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL27223224 | 0.78 | ABCB1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL23043429 | 0.78 | ABCB1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3306426 | 0.77 | RORC (0.36) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099695-A1 | HCV NS3 Protease Inhibitors | MSD ITALIA S.R.L. (IT) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099695-A1 | HCV NS3 Protease Inhibitors | HAVCR2, GTF3C3, CTSC | NR1H2 1166/4885MEN1 4761/4885ALDH1A1 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.