SCHEMBL77331

SCHEMBL77331

CCOC(=O)CC(=O)C(F)(F)F

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.61
MGAM O43451 1/20 0.61
SI P14410 1/20 0.61
MGAM2 Q2M2H8 1/20 0.61
ALDH1A1 P00352 3/20 0.44
TRPA1 O75762 1/20 0.44
FAAH O00519 8/20 0.40
POLB P06746 1/20 0.40
CES1 P23141 5/20 0.39
CES2 O00748 3/20 0.39
CYP1A2 P05177 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3265478 0.98 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7406648 0.98 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7210415 0.98 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
Water SCHEMBL10546276 0.98 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL5149685 0.96 GAA (0.56) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL5148170 0.92 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL25223809 0.90 GAA (0.54) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL2157670 0.89 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL6248725 0.84 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL15286697 0.84 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3307 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036534-A Synthetic method and raw material recovery method of enamine compound 山东潍坊润丰化工股份有限公司 2026-05-15 CN claimed
WO-2026087561-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS SIKA TECHNOLOGY AG (CH) 2026-04-30 WO claimed
EP-4733284-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS Sika Technology AG (CH) 2026-04-29 EP claimed
EP-4702029-A1 CATALYSTS FOR ROOM TEMPERATURE VULCANISABLE (RTV) SILICONE COMPOSITIONS Dow Silicones Corporation (US) 2026-03-04 EP claimed
EP-4702030-A1 CATALYSTS FOR ROOM TEMPERATURE VULCANISABLE (RTV) SILICONE COMPOSITIONS Dow Silicones Corporation (US) 2026-03-04 EP claimed
CN-120149502-A Secondary battery 珠海冠宇电池股份有限公司 2025-06-13 CN claimed
CN-116410138-B Pyricularia sulfone Synthesis method of intermediate 山东润博生物科技有限公司 2025-05-06 CN claimed
CN-119930957-A Trifluoro acetyl piperazine modified polyarylpiperidine film, preparation method thereof and application thereof in neutral organic flow battery 中盐金坛盐化有限责任公司 2025-05-06 CN claimed
US-20250115560-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES ADAMA AGAN LTD (IL) 2025-04-10 US claimed
CN-115850178-B Preparation method of 1-methyl-3- (trifluoromethyl) -1H-pyrazol-5-ol 宁夏格瑞精细化工有限公司 2025-04-04 CN claimed
EP-0158399-B1 LIQUID COATING COMPOSITION FOR PRODUCING HIGH QUALITY, HIGH PERFORMANCE FLUORINE-DOPED TIN OXIDE COATINGS M & T CHEMICALS, INC. (US) 1988-11-02 EP claimed
EP-0206953-B1 PROCESS FOR THE PREPARATION OF ETHYL TRIFLUOROACETOACETATE RHONE-POULENC CHIMIE (FR) 1988-09-07 EP claimed
EP-0270724-A1 Preparation of alkyl trifluoroacetoacetate Monsanto Company (US) 1988-06-15 EP claimed
US-4731256-A Liquid coating composition for producing high quality, high performance fluorine-doped tin oxide coatings M&T CHEMICALS INC. (US) 1988-03-15 US claimed
US-4696837-A Chemical vapor deposition method of producing fluorine-doped tin oxide coatings M&T CHEMICALS INC. (US) 1987-09-29 US claimed
US-4647689-A Preparation of alkyl trifluoroacetoacetate MONSANTO COMPANY (US) 1987-03-03 US claimed
US-4601917-A CHEMICAL VAPOR DEPOSITION M&T CHEMICALS INC. (US) 1986-07-22 US claimed
US-4590096-A USING ORGANOTIN COMPOUND AND ORGANIC FLUORINE DOPANT-CONTROLLING HUMIDITY OF CARRIER GAS STREAM M&T CHEMICALS INC. (US) 1986-05-20 US claimed
EP-0135491-A1 Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters MONSANTO COMPANY (US) 1985-03-27 EP claimed
US-4026898-A 7-Oxo-1,2,3,3,8-pentamethyl-5-trifluoromethyl-2,3,7,8-tetrahydro-1-H-pyrrolo[3,2-g]q THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-05-31 US claimed