Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77331 | 0.90 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7406648 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Water SCHEMBL10546276 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3265478 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7210415 | 0.88 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5149685 | 0.86 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27165197 | 0.85 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL24023255 | 0.83 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL155563 | 0.82 | GAA (0.78) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5148170 | 0.82 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4649076-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-19 | — | — | EP | disclosed |
| US-20250340528-A1 | TARGETED PROTEIN DEGRADATION | MONTE ROSA THERAPEUTICS AG (CH) | 2025-11-06 | — | — | US | disclosed |
| US-12459920-B2 | Targeted protein degradation | MONTE ROSA THERAPEUTICS AG (CH) | 2025-11-04 | — | — | US | disclosed |
| EP-4441041-B1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| US-20250243180-A1 | TARGETED PROTEIN DEGRADATION | MONTE ROSA THERAPEUTICS AG (CH) | 2025-07-31 | — | — | US | disclosed |
| EP-4581022-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-07-09 | — | — | EP | disclosed |
| WO-2025098854-A1 | 5-MEMBERED HETEROARYL AND PYRAZOLE HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2025-05-15 | — | — | WO | disclosed |
| US-20250042876-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-06 | — | — | US | disclosed |
| WO-2025024521-A1 | SUBSTITUTED PIPERIDINEDIONES FOR TARGETED PROTEIN DEGRADATION | MONTE ROSA THERAPEUTICS, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| EP-4441041-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2024-10-09 | — | — | EP | disclosed |
| WO-2024149676-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024149676-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024046890-A1 | HERBICIDAL PYRAZOLE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023099354-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023099354-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243180-A1 | TARGETED PROTEIN DEGRADATION | NEK7, NEK1, RIPK1 | GAA 2474/4885MGAM 4341/4885SI 2489/4885 |
| US-12459920-B2 | Targeted protein degradation | NEK7, NEK1, RIPK1 | GAA 2454/4885MGAM 4334/4885SI 2479/4885 |
| US-20250042876-A1 | HERBICIDAL PYRAZOLE PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHX35 | GAA 1589/4885MGAM 2769/4885SI 4276/4885 |
| US-20250340528-A1 | TARGETED PROTEIN DEGRADATION | NEK7, NEK1, RIPK1 | GAA 2474/4885MGAM 4341/4885SI 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.