SCHEMBL7733186

SCHEMBL7733186

CCCCc1cc(F)c(C(F)(F)Oc2cc(F)c(OC(F)(F)F)c(F)c2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.33
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722892 0.96 PTGS2 (0.38) PTGS2
SCHEMBL7732936 0.92
SCHEMBL7732500 0.92 HDAC3 (0.33)
SCHEMBL7722843 0.90 DAO (0.36) HPGDMAPK1
SCHEMBL18747406 0.89
SCHEMBL18747178 0.89
SCHEMBL18747267 0.89
SCHEMBL7722918 0.88 HDAC3 (0.33) PTGS2
SCHEMBL7732787 0.88 FFAR4 (0.35) APLNR
SCHEMBL7730038 0.87 DAO (0.37) PTGS2NPC1HPGDMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed