SCHEMBL7733232

SCHEMBL7733232

CCCCCCCCCCCCC[PH3+].Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581617 1.00 TSHR (0.36) TSHRTHRB
SCHEMBL25206688 1.00 TSHR (0.36) TSHRTHRB
SCHEMBL3010797 0.95 TSHR (0.33) TSHRTHRB
Octane SCHEMBL29076189 0.93 TSHR (0.42) TSHRTHRB
Octane SCHEMBL23754699 0.91 TSHR (0.40) TSHRTHRB
SCHEMBL4014503 0.85
Octacosanol SCHEMBL30958369 0.83 LMNA (0.54) TSHRTHRB
Decylamine SCHEMBL25432939 0.83 DNM1 (0.54) TSHRTHRB
Dodecylamine SCHEMBL21176121 0.83 DNM1 (0.54) TSHRTHRB
SCHEMBL3922022 0.83 DNM1 (0.54) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912646-B1 HOT MELT ADHESIVES DOW CHEMICAL CO (US) 2002-11-27 EP disclosed
US-6420507-B1 COORDINATION CATALYSTS FOR POLYMERS THE DOW CHEMICAL COMPANY 2002-07-16 US disclosed
US-6319979-B1 HAVING A DENSITY OF 0.850-0.895 G/CM.3 ; TACKIFYING RESIN; AND UP TO 40 WEIGHT PERCENT OF AT LEAST ONE WAX, VISCOSITY OF LESS THAN ABOUT 5000 CPS (50 GRAMS/(CM.SECOND)) AT 150 DEGREES C. THE DOW CHEMICAL COMPANY 2001-11-20 US disclosed