Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731872 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BUTS2RHCRTR1TDP1 | |
| SCHEMBL7733583 | 0.84 | TSHR (0.49) | MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7733440 | 0.84 | TSHR (0.49) | MTNR1AMTNR1BL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7733582 | 0.82 | MEN1 (0.54) | MTNR1AMTNR1BTDP1NPC1RAB9A | |
| SCHEMBL7733837 | 0.82 | MEN1 (0.54) | MTNR1AMTNR1BTDP1NPC1RAB9A | |
| SCHEMBL7723794 | 0.81 | MEN1 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL7736428 | 0.81 | MEN1 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL7734496 | 0.80 | ADORA2A (0.46) | UTS2RL3MBTL1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL7733835 | 0.80 | ADORA2A (0.46) | UTS2RL3MBTL1ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL7733853 | 0.79 | UTS2R (0.49) | MTNR1AMTNR1BUTS2RHCRTR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |