Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14334943 | 0.82 | TDP1 (0.46) | UTS2RMMP9MTNR1AMTNR1BHCRTR1 | |
| SCHEMBL28510176 | 0.80 | UTS2R (0.46) | UTS2RMMP9MTNR1AMTNR1BHCRTR1 | |
| SCHEMBL1320898 | 0.80 | KDM4E (0.52) | UTS2R | |
| SCHEMBL186238 | 0.80 | LMNA (0.61) | TDP1 | |
| SCHEMBL186230 | 0.80 | LMNA (0.61) | TDP1 | |
| SCHEMBL186416 | 0.80 | LMNA (0.61) | TDP1 | |
| SCHEMBL7733336 | 0.79 | MTNR1A (0.47) | UTS2RMMP9MTNR1AMTNR1BHCRTR1 | |
| SCHEMBL7731872 | 0.79 | MTNR1A (0.47) | UTS2RMMP9MTNR1AMTNR1BHCRTR1 | |
| SCHEMBL7734521 | 0.79 | MMP9 (0.69) | MMP9HCRTR1TDP1NPC1HSP90AA1 | |
| SCHEMBL14986294 | 0.79 | MMP9 (0.69) | MMP9HCRTR1TDP1NPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |