Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733349 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7732360 | 0.94 | TRPC3 (0.35) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7732355 | 0.94 | TRPC3 (0.35) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7722576 | 0.93 | TRPC3 (0.35) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7722579 | 0.93 | TRPC3 (0.35) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7730524 | 0.93 | TRPC3 (0.36) | TRPC3TRPC6TRPV4ARCYP11B1 | |
| SCHEMBL7730519 | 0.93 | TRPC3 (0.36) | TRPC3TRPC6TRPV4ARCYP11B1 | |
| SCHEMBL7729700 | 0.88 | TRPV4 (0.35) | TRPV4ARCYP11B1CYP11B2AOC3 | |
| SCHEMBL7729698 | 0.88 | TRPV4 (0.35) | TRPV4ARCYP11B1CYP11B2AOC3 | |
| SCHEMBL7734965 | 0.87 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |