SCHEMBL7733451

SCHEMBL7733451

CCCc1ccc(C(F)(F)Oc2ccc(C(F)(F)Oc3cc(F)c(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
DAO P14920 1/20 0.30
MAOB P27338 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14226653 0.96 KIF11 (0.33) MAOBKIF11
SCHEMBL7731530 0.93 S1PR1 (0.33) FFAR1KIF11
SCHEMBL15317517 0.92 FFAR1 (0.33) FFAR1DAOMAOBKIF11
SCHEMBL7731510 0.92 DAO (0.34) FFAR1DAOMAOBKIF11
SCHEMBL7730380 0.92 S1PR1 (0.35)
SCHEMBL14226542 0.91 KIF11 (0.38) MAOBKIF11
SCHEMBL7722652 0.91 FFAR1 (0.32) FFAR1DAO
SCHEMBL15317518 0.90 MAOA (0.32) FFAR1DAOMAOBKIF11
SCHEMBL7735122 0.90 TSHR (0.32) FFAR1MAOBKIF11
SCHEMBL7733542 0.90 MAOB (0.35) DAOMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed