SCHEMBL7733694

SCHEMBL7733694

CC=CC=CCOc1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP17A1 P05093 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
RARA P10276 1/20 0.35
RARB P10826 1/20 0.35
MAOB P27338 5/20 0.34
MAOA P21397 2/20 0.34
CHRNA7 P36544 3/20 0.33
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
GRM5 P41594 1/20 0.33
AOC3 Q16853 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733688 1.00 POLB (0.37) POLBL3MBTL1CYP17A1CYP11B1CYP11B2
SCHEMBL7733657 0.88 MAOB (0.35) RARARARBMAOB
SCHEMBL7733655 0.88 MAOB (0.35) RARARARBMAOB
SCHEMBL7734389 0.86 AOC3 (0.37) MAOBCHRNA7AOC3
SCHEMBL7734386 0.86 AOC3 (0.37) MAOBCHRNA7AOC3
SCHEMBL7731759 0.84 CYP1A2 (0.36) L3MBTL1MAOBMAOAGRM5
SCHEMBL7731756 0.84 CYP1A2 (0.36) L3MBTL1MAOBMAOAGRM5
SCHEMBL7733103 0.82 AOC3 (0.35) MAOBCHRNA7AOC3
SCHEMBL7733105 0.82 AOC3 (0.35) MAOBCHRNA7AOC3
SCHEMBL7723537 0.81 LSS (0.39) MAOBCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929508-B1 LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS QINETIQ LTD (GB) 2002-03-20 EP disclosed
US-6106908-A OPTICAL APPARATUS WITH LIQUID CRYSTAL COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 2000-08-22 US disclosed