Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 5/20 | 0.34 |
| ▸ | METAP1 | P53582 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735956 | 0.86 | S1PR1 (0.39) | HPGDNPC1NFKB1STAT1RAB9A | |
| SCHEMBL7731411 | 0.81 | HPGD (0.51) | HPGDNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL7735562 | 0.72 | S1PR1 (0.39) | HPGDNPC1NFKB1STAT1RAB9A | |
| Hydrochloric Acid SCHEMBL7347434 | 0.67 | HPGD (0.52) | HPGDNPC1NFKB1RAB9ANFKB2 | |
| Hydrochloric Acid SCHEMBL6356550 | 0.67 | HPGD (0.52) | HPGDNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL7730593 | 0.66 | AAK1 (0.49) | HPGDNPC1NFKB1STAT1RAB9A | |
| SCHEMBL6632792 | 0.66 | LOXL2 (0.56) | HPGDNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL7735961 | 0.65 | LOXL2 (0.51) | HPGDNPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL7733999 | 0.64 | IDO1 (0.43) | HPGDNPC1RAB9AMETAP2METAP1 | |
| SCHEMBL6651863 | 0.64 | LOXL2 (0.60) | HPGDNPC1RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |