Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735956 | 0.85 | S1PR1 (0.39) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL7347434 | 0.85 | HPGD (0.52) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL6356550 | 0.85 | HPGD (0.52) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL6632792 | 0.83 | LOXL2 (0.56) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL7735961 | 0.83 | LOXL2 (0.51) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL6651861 | 0.81 | LOXL2 (0.60) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL6651863 | 0.81 | LOXL2 (0.60) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL6651670 | 0.81 | LOXL2 (0.60) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL7733803 | 0.81 | HPGD (0.35) | HPGDCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL7363930 | 0.78 | LOXL2 (0.60) | HPGDCYP1A2CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |