SCHEMBL7733838

SCHEMBL7733838

CCOC(=O)[C@@H]1CCCC2CCCCC21

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PPM1B O75688 1/20 0.37
PTPN1 P18031 1/20 0.37
PPP1CC P36873 1/20 0.37
MAPT P10636 2/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
FKBP1A P62942 1/20 0.35
TLR4 O00206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3003560 1.00 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4MEN1KMT2A
SCHEMBL14870941 0.98 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MEN1KMT2A
SCHEMBL31017143 0.93 ALDH1A1 (0.37) ALDH1A1MEN1KMT2APPM1BPTPN1
SCHEMBL417314 0.93 ALDH1A1 (0.37) ALDH1A1MEN1KMT2APPM1BPTPN1
SCHEMBL15800125 0.89 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4MEN1KMT2A
SCHEMBL15800134 0.87 ALDH1A1 (0.34) ALDH1A1TP53CYP3A4KMT2APPM1B
SCHEMBL14870925 0.87 ALDH1A1 (0.34) ALDH1A1TP53CYP3A4KMT2APPM1B
SCHEMBL5791354 0.86 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4MEN1KMT2A
SCHEMBL2997415 0.83 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4
SCHEMBL594647 0.82 TP53 (0.48) ALDH1A1TP53CYP3A4PPM1BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0990634-B1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES DAICEL CHEM (JP) 2013-04-10 EP disclosed
US-6429314-B1 USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-06 US disclosed
EP-0990634-A1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES Daicel Chemical Industries, Ltd. (JP) 2000-04-05 EP disclosed