Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733838 | 0.98 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL3003560 | 0.98 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL31017143 | 0.91 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2APPM1BPTPN1 | |
| SCHEMBL417314 | 0.91 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2APPM1BPTPN1 | |
| SCHEMBL15800125 | 0.87 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL15800134 | 0.85 | ALDH1A1 (0.34) | ALDH1A1KMT2ATP53CYP3A4PPM1B | |
| SCHEMBL14870925 | 0.85 | ALDH1A1 (0.34) | ALDH1A1KMT2ATP53CYP3A4PPM1B | |
| SCHEMBL5750749 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL5750745 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL5791354 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754252-B2 | Asymmetric cyclization processes using unsaturated nitro compounds | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-06-17 | — | — | US | disclosed |
| US-20130096338-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096338-A1 | ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS | NQO1, COASY, NOS2 | ALDH1A1 2383/4885MEN1 3219/4885KMT2A 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.