Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12040648 | 0.90 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL25797045 | 0.88 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7732089 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL3176190 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL29556577 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2062270 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL3957309 | 0.83 | ALDH1A1 (0.70) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL20591963 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL15540034 | 0.83 | DRD2 (0.52) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL25796957 | 0.82 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |