Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7734068

NCc1ccc(-c2ccccc2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.67
HRH3 Q9Y5N1 1/20 0.52
FFAR1 O14842 1/20 0.52
BACE1 P56817 4/20 0.50
TSHR P16473 2/20 0.50
BACE2 Q9Y5Z0 2/20 0.50
ABCC4 O15439 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
HDAC1 Q13547 1/20 0.48
SRR Q9GZT4 2/20 0.47
PSAT1 Q9Y617 2/20 0.47
LOXL2 Q9Y4K0 1/20 0.46
HTR5A P47898 1/20 0.45
SLC13A5 Q86YT5 1/20 0.45
CYP2C9 P11712 2/20 0.44
CYP2A6 P11509 1/20 0.44
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylamine SCHEMBL5450068 0.88 LOXL2 (0.61) TAAR1TSHRPTGS1LOXL2CYP2C9
Trifluoroacetic Acid SCHEMBL12611414 0.84 CES1 (0.52) FFAR1HDAC1CYP2C9CES1
Acetic Acid SCHEMBL4936110 0.82 TAAR1 (0.75) TAAR1HRH3FFAR1BACE1TSHR
Trifluoroacetic Acid SCHEMBL7451670 0.82 CA12 (0.53) GAACYP1A2
SCHEMBL22291708 0.82 TAAR1 (1.00) TAAR1HRH3TSHRABCC4LMNA
SCHEMBL28208288 0.82 TAAR1 (1.00) TAAR1HRH3TSHRABCC4LMNA
SCHEMBL131842 0.82 TAAR1 (1.00) TAAR1HRH3TSHRABCC4LMNA
SCHEMBL22202237 0.82 TAAR1 (1.00) TAAR1HRH3TSHRABCC4LMNA
Biphenyl SCHEMBL27461116 0.82 CES1 (0.54) FFAR1TSHRABCC4LMNAGAA
Trifluoroacetic Acid SCHEMBL3507985 0.81 ADRB2 (0.46) TAAR1FFAR1LOXL2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399629-B1 PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY MICROCIDE PHARMACEUTICALS, INC. 2002-06-04 US disclosed
WO-2000001714-A1 EFFLUX PUMP INHIBITORS MICROCIDE PHARMACEUTICALS, INC. (US) 2000-01-13 WO disclosed