⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722291 | 0.94 | — | — | |
| SCHEMBL7729968 | 0.94 | — | — | |
| SCHEMBL7732382 | 0.92 | — | — | |
| SCHEMBL7722337 | 0.86 | FAP (0.35) | — | |
| SCHEMBL7722376 | 0.86 | — | — | |
| SCHEMBL7730735 | 0.84 | FAP (0.35) | — | |
| SCHEMBL6893546 | 0.83 | CACNA1C (0.35) | — | |
| SCHEMBL6886821 | 0.83 | CACNA1C (0.35) | — | |
| SCHEMBL6887231 | 0.83 | CACNA1C (0.35) | — | |
| SCHEMBL6893817 | 0.83 | CACNA1C (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |