Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732992 | 0.84 | NQO2 (0.42) | TDP1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8696985 | 0.75 | TAAR1 (0.46) | SLC6A4SLC6A3SLC6A2TDP1TAAR1 | |
| SCHEMBL27612097 | 0.70 | ALDH1A1 (0.45) | SLC6A4SLC6A3SLC6A2TDP1TAAR1 | |
| SCHEMBL8347572 | 0.69 | TAAR1 (0.42) | SLC6A4SLC6A3SLC6A2TAAR1FFAR1 | |
| SCHEMBL8349629 | 0.68 | TAAR1 (0.47) | SLC6A4SLC6A3SLC6A2TAAR1HDAC1 | |
| SCHEMBL5312097 | 0.67 | TAAR1 (0.46) | SLC6A4SLC6A3SLC6A2TDP1TAAR1 | |
| SCHEMBL8346288 | 0.67 | TAAR1 (0.45) | SLC6A4SLC6A3SLC6A2TDP1TAAR1 | |
| SCHEMBL7861192 | 0.66 | NQO2 (0.60) | TDP1TAAR1ALDH1A1F2F10 | |
| SCHEMBL8345399 | 0.65 | HDAC3 (0.41) | SLC6A4SLC6A3SLC6A2TAAR1HDAC6 | |
| Hydrochloric Acid SCHEMBL9079642 | 0.65 | TOP2A (0.61) | TDP1TAAR1ALDH1A1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792271-B1 | FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM | UNIV GEORGIA STATE RES FOUND (US) | 2002-02-27 | — | — | EP | claimed |