Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394160 | 1.00 | CES2 (0.41) | CES2CES1TRPA1DPP4TSHR | |
| SCHEMBL8728321 | 0.78 | ALDH1A1 (0.33) | CES2CES1TRPA1TSHRALDH1A1 | |
| SCHEMBL10590024 | 0.78 | CES2 (0.44) | CES2CES1TRPA1DPP4TSHR | |
| SCHEMBL28477107 | 0.77 | CYP2A6 (0.40) | DPP4ALDH1A1HSD17B10HTR2ACYP2D6 | |
| SCHEMBL14321447 | 0.77 | IDO1 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL14321076 | 0.75 | CHRNA7 (0.39) | TSHRALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL5866912 | 0.75 | GSK3B (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL14321453 | 0.75 | TSHR (0.44) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL29488208 | 0.75 | HDAC4 (0.42) | CES2CES1 | |
| SCHEMBL14321085 | 0.75 | HDAC4 (0.42) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 450 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264013-A | Preparation method of (1-arylmethyl-3-aryl-1-trifluoromethyl propyl) aromatic compound | 南京工业大学 | 2025-01-07 | — | — | CN | claimed |
| CN-118344340-A | Quinolinone compound containing 1,2, 4-triazole or 1,3, 4-oxadiazole structure and preparation and application thereof | 贵州大学 | 2024-07-16 | — | — | CN | claimed |
| CN-117486852-A | Fluorine-containing rotaxane molecule and preparation method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2024-02-02 | — | — | CN | claimed |
| CN-114806260-B | Preparation method of modified nano zinc oxide filler, hydrophobic antifouling coating and preparation method thereof | 海南大学 | 2023-02-28 | — | — | CN | claimed |
| CN-114988981-A | Preparation method of alpha-trifluoromethyl arylpropyne compound | 盐城工学院 | 2022-09-02 | — | — | CN | claimed |
| CN-113549062-B | Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof | 南京工业大学 | 2022-08-09 | — | — | CN | claimed |
| CN-114806260-A | Preparation method of modified nano zinc oxide filler, hydrophobic antifouling coating and preparation method thereof | 海南大学 | 2022-07-29 | — | — | CN | claimed |
| CN-108395396-B | Preparation method of chiral o-amino alcohol intermediate, antagonist and analogue thereof | 复旦大学 | 2021-07-23 | — | — | CN | claimed |
| CN-109438461-B | Tuliquiritigenin A derivative with anti-leukemia activity and preparation method and application thereof | 广西中医药大学 | 2021-04-20 | — | — | CN | claimed |
| CN-104987338-A | Low cost method for preparing sitagliptin phosphate salt key intermediate | XINFA PHARMACEUTICAL CO LTD | 2015-10-21 | — | — | CN | claimed |
| US-8901365-B2 | Catalytic Wittig and Mitsunobu reactions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-12-02 | — | — | US | claimed |
| CN-100569746-C | Arylbis (perfluoroalkylsulfonyl) methane and metal salts thereof, and process for producing the same | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-12-16 | — | — | CN | claimed |
| CN-1481357-A | Arylbis (perfluoroalkylsulfonyl) methane and metal salts thereof, and process for producing the same | 科学技术振兴事业团 | 2004-03-10 | — | — | CN | claimed |
| WO-2025120200-A1 | NEW ANTI-INFECTIVE TRICYCLIC SPIROLACTAMS COMPOUNDS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2025-06-12 | — | — | WO | disclosed |
| CN-119264013-A | Preparation method of (1-arylmethyl-3-aryl-1-trifluoromethyl propyl) aromatic compound | 南京工业大学 | 2025-01-07 | — | — | CN | disclosed |
| WO-2024230104-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 浙江同源康医药股份有限公司 | 2024-11-14 | — | — | WO | disclosed |
| US-5248689-A | Hypotensive agents, congestive heart failure, renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-28 | — | — | US | disclosed |
| WO-1993001160-A1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| US-4966987-A | CHEMICAL INTERMEDIATE FOR FLUORINATED AROMATIC COMPOUND | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4132737-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1979-01-02 | — | — | US | disclosed |