Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21757441 | 0.80 | TDP1 (0.33) | TDP1LMNAL3MBTL1PPARGPPARD | |
| SCHEMBL25054478 | 0.79 | TDP1 (0.36) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL5344355 | 0.75 | TSHR (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL22574870 | 0.74 | TDP1 (0.36) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL2306637 | 0.74 | TSHR (0.41) | TDP1LMNAL3MBTL1TSHRKDM4E | |
| SCHEMBL12663200 | 0.72 | TDP1 (0.40) | TDP1LMNAL3MBTL1PPARGPPARD | |
| SCHEMBL60554 | 0.72 | — | — | |
| SCHEMBL283630 | 0.72 | — | — | |
| SCHEMBL1089459 | 0.72 | — | — | |
| SCHEMBL12330492 | 0.71 | LMNA (0.42) | TDP1LMNAL3MBTL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399049-B1 | LIQUID 1,2-HYDROXYALKYL AMIDE, ESTER, ETHER, SILICONE OR ALKYL COMPOUND CARRIERS; NONIRRITATING; | THE PROCTER & GAMBLE COMPANY | 2002-06-04 | — | — | US | disclosed |