Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732832 | 0.94 | KIF11 (0.36) | KIF11CTSSCTSKALDH1A1MAPT | |
| SCHEMBL7731170 | 0.93 | TSHR (0.41) | KIF11ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7732827 | 0.91 | KIF11 (0.39) | KIF11ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7729800 | 0.91 | AR (0.33) | CTSSCTSKALDH1A1MAPTMEN1 | |
| SCHEMBL7731508 | 0.88 | AR (0.32) | ALDH1A1ARKDM4EGLAGAA | |
| SCHEMBL7732570 | 0.87 | KIF11 (0.39) | KIF11CYP11B1CYP11B2FFAR1 | |
| SCHEMBL7722816 | 0.86 | CTSS (0.33) | KIF11CTSSCTSKALDH1A1MAPT | |
| SCHEMBL7730680 | 0.86 | MEN1 (0.37) | KIF11CTSSCTSKALDH1A1MAPT | |
| SCHEMBL7728933 | 0.86 | KIF11 (0.41) | KIF11CYP11B1CYP11B2FFAR1 | |
| SCHEMBL12623087 | 0.85 | RARB (0.37) | KIF11ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |