Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | MMP12 | P39900 | 4/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734967 | 1.00 | EGLN1 (0.37) | EGLN1MMP2MMP9MMP12ACACB | |
| SCHEMBL7742692 | 0.94 | HDAC1 (0.36) | EGLN1MMP2MMP9MMP12ACACB | |
| SCHEMBL7742697 | 0.94 | HDAC1 (0.36) | EGLN1MMP2MMP9MMP12ACACB | |
| SCHEMBL7741260 | 0.91 | TAS1R3 (0.36) | ACACB | |
| SCHEMBL7741257 | 0.91 | TAS1R3 (0.36) | ACACB | |
| SCHEMBL7742595 | 0.91 | TAS1R3 (0.36) | ACACB | |
| SCHEMBL7734918 | 0.89 | MMP2 (0.44) | MMP2MMP12ACACB | |
| SCHEMBL7734920 | 0.89 | MMP2 (0.44) | MMP2MMP12ACACB | |
| SCHEMBL7739798 | 0.86 | MMP2 (0.44) | MMP2MMP12 | |
| SCHEMBL7739789 | 0.86 | MMP2 (0.44) | MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |