SCHEMBL7735287

SCHEMBL7735287

CCCCSC(=O)C(=O)SC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CES1 P23141 6/20 0.36
TDP1 Q9NUW8 1/20 0.36
CES2 O00748 6/20 0.35
TP53 P04637 2/20 0.34
GMNN O75496 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
CYP2C9 P11712 1/20 0.34
BLM P54132 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ACHE P22303 3/20 0.34
AKR1B1 P15121 1/20 0.32
EPHX1 P07099 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7742844 0.78
SCHEMBL6131318 0.74 NOS3 (0.41) ALDH1A1NOS3NOS1NOS2NPSR1
SCHEMBL6136620 0.74 NOS3 (0.50) ALDH1A1NOS3NOS1NOS2NPSR1
SCHEMBL11143545 0.72 NOS3 (0.48) ALDH1A1NOS3NOS1NOS2NPSR1
SCHEMBL2736682 0.72
SCHEMBL2829403 0.72
SCHEMBL6234311 0.72
SCHEMBL148183 0.72 NOS3 (0.48) ALDH1A1NOS3NOS1NOS2NPSR1
SCHEMBL6960158 0.72
SCHEMBL8657099 0.72 NOS3 (0.48) ALDH1A1NOS3NOS1NOS2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413677-B1 THIOCARBONATE ELECTROLYTE UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed