SCHEMBL7735343

SCHEMBL7735343

COC(=O)CCCc1ccc(OC2CCCC2)c(-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.47
PDE4D Q08499 10/20 0.43
PDE4B Q07343 9/20 0.43
PDE4A P27815 9/20 0.43
PDE4C Q08493 8/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
RECQL P46063 1/20 0.41
PLAAT3 P53816 1/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT2 Q9NWW9 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40
HPGD P15428 1/20 0.40
ITGB1 P05556 1/20 0.40
ITGA4 P13612 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733983 0.99 PTPN1 (0.46) PTPN1PDE4DPDE4BPDE4APDE4C
SCHEMBL27536403 0.93 PTPN1 (0.54) PTPN1PDE4DPDE4BPDE4APDE4C
SCHEMBL7735879 0.92 PTPN1 (0.53) PTPN1PDE4DPDE4BPDE4APDE4C
SCHEMBL7725094 0.89 FFAR4 (0.49) HDAC1HDAC2
SCHEMBL7735139 0.88 FFAR4 (0.48) HDAC1HDAC2
SCHEMBL7734891 0.85 C5AR1 (0.51) PTPN1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL7734075 0.84 C5AR1 (0.52) PTPN1
SCHEMBL7733967 0.84 FFAR4 (0.50) PDE4DPDE4BPDE4APDE4CHDAC1
SCHEMBL7735763 0.84 PTPN1 (0.54) PTPN1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL7735708 0.83 THRA (0.52) PDE4DPDE4BPDE4APDE4CHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed