Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.44 |
| ▸ | PDE4A | P27815 | 8/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536403 | 0.99 | PTPN1 (0.54) | PTPN1HDAC1HDAC2PDE4BPDE4D | |
| SCHEMBL7733983 | 0.94 | PTPN1 (0.46) | PTPN1HDAC1HDAC2PDE4BPDE4D | |
| SCHEMBL7735343 | 0.92 | PTPN1 (0.47) | PTPN1HDAC1HDAC2PDE4BPDE4D | |
| SCHEMBL3886842 | 0.89 | CCNC (0.48) | PTPN1HDAC1HDAC2PDE4BPDE4D | |
| SCHEMBL7735708 | 0.89 | THRA (0.52) | HDAC1HDAC2PDE4BPDE4DPDE4A | |
| SCHEMBL3684452 | 0.87 | CCNC (0.49) | PTPN1HDAC1HDAC2PDE4BPDE4D | |
| SCHEMBL7733967 | 0.87 | FFAR4 (0.50) | HDAC1HDAC2PDE4BPDE4DPDE4A | |
| SCHEMBL7725535 | 0.85 | C5AR1 (0.57) | PTPN1MEN1KMT2AHRH3THRA | |
| SCHEMBL7735139 | 0.84 | FFAR4 (0.48) | HDAC1HDAC2THRATHRB | |
| SCHEMBL7725141 | 0.83 | C5AR1 (0.55) | PTPN1MEN1KMT2AHRH3THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |