Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735377 | 1.00 | CCR2 (0.32) | CCR2ESR2HTR2CDGAT1SOAT1 | |
| SCHEMBL12028508 | 0.97 | DGAT1 (0.34) | CCR2ESR2DGAT1SOAT1 | |
| SCHEMBL7732612 | 0.93 | CCR2 (0.33) | CCR2ESR2 | |
| SCHEMBL7732608 | 0.93 | CCR2 (0.33) | CCR2ESR2 | |
| SCHEMBL8370018 | 0.91 | CCR2 (0.34) | CCR2ESR2 | |
| SCHEMBL8370017 | 0.91 | CCR2 (0.34) | CCR2ESR2 | |
| SCHEMBL7730880 | 0.88 | GRM2 (0.30) | — | |
| SCHEMBL7730885 | 0.88 | GRM2 (0.30) | — | |
| SCHEMBL8470877 | 0.87 | CCR2 (0.33) | CCR2ESR2ALDH1A1LMNAMAPT | |
| SCHEMBL7732619 | 0.87 | CCR2 (0.33) | CCR2ESR2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |