Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.51 |
| ▸ | CASP1 | P29466 | 7/20 | 0.48 |
| ▸ | CASP7 | P55210 | 8/20 | 0.47 |
| ▸ | CASP9 | P55211 | 5/20 | 0.47 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 4/20 | 0.46 |
| ▸ | CASP6 | P55212 | 3/20 | 0.46 |
| ▸ | CASP4 | P49662 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CASP5 | P51878 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645918 | 0.89 | CASP3 (0.57) | CASP3CASP1CASP7CASP9CASP10 | |
| SCHEMBL713780 | 0.85 | CASP3 (0.56) | CASP3CASP1CASP7CASP9CASP10 | |
| SCHEMBL2033191 | 0.85 | CASP3 (0.56) | CASP3CASP1CASP7CASP9CASP10 | |
| SCHEMBL8247253 | 0.83 | CASP3 (0.67) | CASP3CASP1CASP8CASP6 | |
| SCHEMBL8402109 | 0.83 | CASP1 (0.59) | CASP3CASP1CASP7CASP9CASP8 | |
| SCHEMBL13197161 | 0.83 | CASP1 (0.59) | CASP3CASP1CASP7CASP9CASP8 | |
| SCHEMBL7745119 | 0.83 | CASP3 (0.67) | CASP3CASP1CASP8CASP6 | |
| SCHEMBL12946446 | 0.83 | CASP1 (0.59) | CASP3CASP1CASP7CASP9CASP8 | |
| SCHEMBL949009 | 0.83 | CASP1 (0.59) | CASP3CASP1CASP7CASP9CASP8 | |
| SCHEMBL614741 | 0.82 | CASP3 (0.62) | CASP3CASP1CASP7CASP9CASP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423840-B1 | FORMING N-ACYLAMINO COMPOUND | VERTEX PHARMACEUTICALS INCORPORATED | 2002-07-23 | — | — | US | disclosed |