Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30726485 | 0.91 | KMT2A (0.53) | KMT2AMEN1NCEH1MAPTALDH1A1 | |
| SCHEMBL3406179 | 0.91 | KMT2A (0.53) | KMT2AMEN1NCEH1MAPTALDH1A1 | |
| SCHEMBL6637953 | 0.83 | MTNR1A (0.60) | CYP1A2CYP2C19ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11000179 | 0.82 | ALDH1A1 (0.61) | KMT2AMEN1MAPTALDH1A1LMNA | |
| Methane SCHEMBL8679956 | 0.81 | ALDH1A1 (0.59) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL27329722 | 0.80 | NCEH1 (0.62) | KMT2AMEN1NCEH1MAPTPOLB | |
| SCHEMBL7821071 | 0.80 | HDAC1 (0.55) | KMT2AMEN1NCEH1 | |
| Acetic Acid SCHEMBL30553976 | 0.80 | SLC6A4 (0.55) | KMT2AMEN1NCEH1MAPTALDH1A1 | |
| SCHEMBL29743344 | 0.79 | SLC6A4 (0.51) | KMT2AMEN1NCEH1MAPTPOLB | |
| SCHEMBL9289234 | 0.79 | NCEH1 (0.57) | KMT2AMEN1NCEH1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247528-C | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | SIRVIR LAB (FR) | 2006-03-29 | — | — | CN | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |