Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725867 | 0.94 | LPAR1 (0.42) | LPAR1 | |
| SCHEMBL7735840 | 0.94 | LPAR1 (0.39) | LPAR1ACAT1 | |
| SCHEMBL7734600 | 0.93 | ACAT1 (0.38) | LPAR1ACAT1 | |
| SCHEMBL7734577 | 0.91 | GRM2 (0.41) | ACAT1 | |
| SCHEMBL7735537 | 0.90 | ACAT1 (0.39) | LPAR1ACAT1 | |
| SCHEMBL7725873 | 0.88 | — | — | |
| SCHEMBL7734408 | 0.86 | HRH3 (0.40) | ACAT1 | |
| SCHEMBL7735806 | 0.85 | GRM2 (0.41) | LPAR1 | |
| SCHEMBL7734497 | 0.85 | MET (0.41) | ACAT1 | |
| SCHEMBL7725879 | 0.85 | LPAR1 (0.46) | LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452008-B2 | 3-UREA COMPOUND FROM THE 3-AMIDO COMPOUND WITHOUT AZIDATION PROCESS WHICH HAS RISK OF EXPLOSION; REACTION WITH HYPOCHLORITE, HYPOBROMITE OR LEAD TETRAACETATE AND THEN AN AMINE; ACAT INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-09-17 | — | — | US | disclosed |
| US-6300500-B1 | Preparation of pyridone derivatives using phthalimido containing starting material | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1086948-A1 | PYRIDONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-28 | — | — | EP | disclosed |