Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725129 | 0.93 | PTPN1 (0.51) | PTPN1AKR1C3KMT2ATP53MDM2 | |
| SCHEMBL7734883 | 0.89 | TP53 (0.52) | AKR1C3TP53MDM2PTGDR2BCL2L1 | |
| SCHEMBL7735390 | 0.87 | PTPN1 (0.55) | PTPN1TP53ADRB2ADRB1ADRB3 | |
| SCHEMBL7734077 | 0.84 | PPARD (0.47) | AKR1C3TP53MDM2PTGDR2BCL2L1 | |
| SCHEMBL7725111 | 0.83 | PTPN1 (0.56) | PTPN1AKR1C3PTGDR2 | |
| SCHEMBL7735881 | 0.83 | PTPN1 (0.56) | PTPN1KMT2ATP53MDM2PTGDR2 | |
| SCHEMBL27403097 | 0.83 | PTPN1 (0.56) | PTPN1KMT2APTGDR2 | |
| SCHEMBL7735299 | 0.83 | PTPN1 (0.48) | PTPN1KMT2APTGDR2 | |
| SCHEMBL27428215 | 0.83 | PTPN1 (0.53) | PTPN1AKR1C3KMT2APTGDR2 | |
| SCHEMBL7734899 | 0.82 | PTPN1 (0.55) | PTPN1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |