SCHEMBL7735299

SCHEMBL7735299

CCC(C)COc1ccc(CCCC(=O)OC)cc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.48
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
PLAAT3 P53816 1/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT2 Q9NWW9 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40
HPGD P15428 1/20 0.40
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
MGLL Q99685 1/20 0.38
KMT2A Q03164 1/20 0.38
GPR88 Q9GZN0 1/20 0.38
C5AR1 P21730 1/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
LTB4R Q15722 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7725129 0.90 PTPN1 (0.51) PTPN1PPARGPPARDPPARAPLAAT3
SCHEMBL7735870 0.90 PPARD (0.47) PPARGPPARDPPARASMN1; SMN2PTGDR2
SCHEMBL7734083 0.89 PTPN1 (0.48) PTPN1PPARGPPARDPPARAPLAAT3
SCHEMBL7735357 0.85 PTPN1 (0.50) PTPN1PPARGPPARDPPARAPLAAT3
SCHEMBL7737515 0.84 THRA (0.49) PTPN1PPARGPPARDPPARAPLAAT3
SCHEMBL7734111 0.84 PTPN1 (0.49) PTPN1PPARGPPARDPPARAPLAAT3
SCHEMBL7737650 0.84 THRA (0.53) PTPN1PPARGPPARAKDM4ESMN1; SMN2
SCHEMBL7735868 0.83 PTPN1 (0.58) PTPN1PTGDR2KMT2A
SCHEMBL7735763 0.83 PTPN1 (0.54) PTPN1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL7735390 0.83 PTPN1 (0.55) PTPN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed