Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | FOS | P01100 | 2/20 | 0.48 |
| ▸ | JUN | P05412 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734077 | 0.93 | PPARD (0.47) | TP53MDM2FFAR4BCL2L1MCL1 | |
| SCHEMBL7735868 | 0.89 | PTPN1 (0.58) | TP53MDM2FFAR4BCL2L1MCL1 | |
| SCHEMBL7735382 | 0.86 | FFAR4 (0.48) | TP53MDM2FFAR4BCL2L1MCL1 | |
| SCHEMBL27406192 | 0.85 | PTGER1 (0.45) | TP53MDM2PPARGPPARDPPARA | |
| SCHEMBL7725129 | 0.84 | PTPN1 (0.51) | TP53MDM2PPARGPPARDPPARA | |
| SCHEMBL7735506 | 0.84 | PTGDR2 (0.63) | TP53MDM2FFAR4BCL2L1MCL1 | |
| SCHEMBL7725124 | 0.82 | FFAR1 (0.58) | TP53MDM2FFAR4FFAR1 | |
| SCHEMBL7735870 | 0.82 | PPARD (0.47) | TP53MDM2FFAR4BCL2L1MCL1 | |
| SCHEMBL7734788 | 0.82 | RXRA (0.53) | FFAR4FFAR1PPARGPPARDPPARA | |
| SCHEMBL7734849 | 0.81 | PTGDR2 (0.53) | TP53MDM2FFAR4BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | claimed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | claimed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | claimed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | claimed |
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |