Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.52 |
| ▸ | RXRG | P48443 | 13/20 | 0.52 |
| ▸ | RXRB | P28702 | 10/20 | 0.52 |
| ▸ | RARG | P13631 | 5/20 | 0.52 |
| ▸ | RARA | P10276 | 4/20 | 0.52 |
| ▸ | RARB | P10826 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735872 | 1.00 | RXRA (0.52) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL7732336 | 0.85 | RXRA (0.45) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL7732340 | 0.85 | RXRA (0.45) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL6915971 | 0.82 | RXRA (0.40) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8005479 | 0.81 | RXRA (0.46) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL6915982 | 0.79 | RXRA (0.41) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL14020532 | 0.79 | RXRA (0.61) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL4146810 | 0.79 | RXRA (0.61) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL4146808 | 0.79 | RXRA (0.61) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL7731135 | 0.78 | RXRA (0.55) | RXRARXRGRXRBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403638-B1 | COMPOUND FOR USE IN TREATING SKIN DISEASES AND DISORDERS, AND FOR TREATING HYPERVITAMINOSIS A SYNDROME | ALLERGAN SALES, INC. | 2002-06-11 | — | — | US | disclosed |