⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768321 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL16689956 | 0.52 | CDK5 (0.32) | — | |
| Potassium SCHEMBL4755261 | 0.52 | CDK5 (0.32) | — | |
| SCHEMBL31112247 | 0.47 | MAOA (0.77) | — | |
| SCHEMBL30956639 | 0.47 | MAOA (0.70) | — | |
| SCHEMBL1604498 | 0.43 | — | — | |
| SCHEMBL4968 | 0.43 | — | — | |
| SCHEMBL1830625 | 0.43 | — | — | |
| SCHEMBL25311994 | 0.41 | — | — | |
| SCHEMBL31290743 | 0.39 | ATM (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230570-B | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2023-02-28 | — | — | CN | claimed |
| CN-114230570-A | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2022-03-25 | — | — | CN | claimed |
| CN-114230570-B | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-114230570-B | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-114230570-B | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-114230570-A | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-114230570-A | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-114230570-A | Pyrrolo [3,4-b ] pyrroledione compounds and synthesis method thereof | 浙江工业大学 | 2022-03-25 | — | — | CN | disclosed |
| US-6409956-B1 | PARTIALLY CRYSTALLINE PLASTICS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-25 | — | — | US | disclosed |