Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728096 | 1.00 | MAPT (0.53) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL1726924 | 1.00 | MAPT (0.53) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL922010 | 0.78 | MAPT (0.62) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL5780462 | 0.77 | NPC1 (0.49) | MAPTGAANPSR1KDM4ERAB9A | |
| SCHEMBL5780459 | 0.77 | NPC1 (0.55) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL5780457 | 0.77 | NPC1 (0.55) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL922712 | 0.75 | MAPT (0.81) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL922713 | 0.75 | MAPT (0.81) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL1767622 | 0.74 | MAPT (0.54) | MAPTGAANPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL17769562 | 0.74 | MAPT (0.54) | MAPTGAANPSR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010039247-A1 | Pesticidal compositions | KARRER FRIEDRICH (CH) | 2001-11-08 | — | — | US | claimed |
| EP-1021398-A1 | PESTICIDAL COMPOSITIONS | Novartis AG (CH) | 2000-07-26 | — | — | EP | claimed |
| WO-1998003475-A1 | PESTICIDAL COMPOSITIONS | NOVARTIS AG (CH) | 1998-01-29 | — | — | WO | claimed |
| US-6417386-B2 | HYDRAZONE DERIVATIVES; ACARINA; MITICIDES | SYNGENTA CROP PROTECTION, INC. | 2002-07-09 | — | — | US | disclosed |
| US-20010039247-A1 | Pesticidal compositions | KARRER FRIEDRICH (CH) | 2001-11-08 | — | — | US | disclosed |
| US-6306798-B1 | Compounds for controlling insects and representatives of the order acarina | SYNGENTA CROP PROTECTION, INC. | 2001-10-23 | — | — | US | disclosed |
| EP-1049663-A1 | ORGANIC NITRILE DERIVATIVES AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 2000-11-08 | — | — | EP | disclosed |
| EP-1021398-A1 | PESTICIDAL COMPOSITIONS | Novartis AG (CH) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999037603-A1 | ORGANIC NITRILE DERIVATIVES AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1999-07-29 | — | — | WO | disclosed |
| WO-1998003475-A1 | PESTICIDAL COMPOSITIONS | NOVARTIS AG (CH) | 1998-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039247-A1 | Pesticidal compositions | MTX1, PEF1, ECH1 | MAPT 88/4885GAA 1504/4885NPSR1 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.