SCHEMBL922010

SCHEMBL922010

N#CC(C#N)=NNc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 16/20 0.62
MEN1 O00255 10/20 0.62
KMT2A Q03164 10/20 0.62
TDP1 Q9NUW8 6/20 0.62
SMN1; SMN2 Q16637 6/20 0.62
CYP3A4 P08684 3/20 0.62
ALOX15 P16050 2/20 0.62
TSHR P16473 2/20 0.62
HSD17B10 Q99714 2/20 0.62
CISD1 Q9NZ45 1/20 0.62
NPSR1 Q6W5P4 7/20 0.58
GAA P10253 3/20 0.58
KDM4E B2RXH2 1/20 0.58
MMP14 P50281 1/20 0.56
CACNA1B Q00975 1/20 0.56
APBA1 Q02410 1/20 0.56
MCL1 Q07820 1/20 0.56
ALDH1A1 P00352 7/20 0.54
HIF1A Q16665 2/20 0.54
TP53 P04637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28310189 0.88 MAPT (0.51) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL24706313 0.88 MAPT (0.54) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL922543 0.84 MAPT (0.60) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL923268 0.80 MAPT (0.59) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL2143882 0.79 MEN1 (0.64) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL923484 0.79 MAPT (0.57) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL2241345 0.79 ALDH1A1 (0.60) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL922178 0.79 MAPT (0.57) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL1767622 0.79 MAPT (0.54) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL17769562 0.79 MAPT (0.54) MAPTMEN1KMT2ATDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110108531-B Method for eliminating blood cell interference in medical detection 深圳天深医疗器械有限公司 2022-02-11 CN claimed
US-20210161937-A1 ACTIVATION OF MITOCHONDRIAL UNCOUPLING AS A THERAPEUTIC INTERVENTION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2021-06-03 US claimed
CN-110108531-A A method of excluding haemocyte interference in medicine detection 深圳天深医疗器械有限公司 2019-08-09 CN claimed
WO-2019147626-A1 ACTIVATION OF MITOCHONDRIAL UNCOUPLING AS A THERAPEUTIC INTERVENTION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-08-01 WO claimed
EP-0461392-B1 Test carrier for the determination of ions BOEHRINGER MANNHEIM GMBH (DE) 1996-01-10 EP claimed
EP-0461392-A2 Test carrier for the determination of ions Roche Diagnostics GmbH (DE) 1991-12-18 EP claimed
US-20260081034-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS EMERJA CORP (US) 2026-03-19 US disclosed
US-20260081035-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS EMERJA CORP (US) 2026-03-19 US disclosed
US-20250382328-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS JENIUS PHARMA LLC (US) 2025-12-18 US disclosed
US-12454549-B2 Treatments for diseases and disorders that involve oxidative stress JENIUS PHARMA, LLC (US) 2025-10-28 US disclosed
US-12312599-B2 Methods, compositions, and kits for producing beige adipocytes and treating metabolic disorders MaineHealth (US) 2025-05-27 US disclosed
EP-4536265-A2 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS Jenius Pharma, LLC (US) 2025-04-16 EP disclosed
US-20240132542-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS Allegro Pharmaceuticals, LLC 2024-04-25 US disclosed
US-5123414-A Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same CITIZENS BANK, N.A. 1992-06-23 US disclosed
US-5088499-A Medical diagnosis CITIZENS BANK, N.A. 1992-02-18 US disclosed
EP-0461392-A2 Test carrier for the determination of ions Roche Diagnostics GmbH (DE) 1991-12-18 EP disclosed
WO-1991009629-A1 LIPOSOMES AS CONTRAST AGENTS FOR ULTRASONIC IMAGING UNGER EVAN C (US) 1991-07-11 WO disclosed
EP-0412211-A1 Cancer therapy system THERAPEUTICAL SYSTEMS CORPORATION (US) 1991-02-13 EP disclosed
US-4935450-A Cancer therapy system for effecting oncolysis of malignant neoplasms THERAPEUTICAL SYSTEMS CORPORATION (US) 1990-06-19 US disclosed
US-4724234-A ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION THERAPEUTICAL SYSTEMS CORP. (US) 1988-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132542-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS GPX4, GPX1, TXNRD2 MAPT 694/4885MEN1 4366/4885KMT2A 4421/4885
US-12454549-B2 Treatments for diseases and disorders that involve oxidative stress GPX4, GPX1, TXNRD2 MAPT 694/4885MEN1 4366/4885KMT2A 4421/4885
US-20250382328-A1 TREATMENTS FOR DISEASES AND DISORDERS THAT INVOLVE OXIDATIVE STRESS GPX4, GPX1, TXNRD2 MAPT 694/4885MEN1 4366/4885KMT2A 4421/4885
US-20260081035-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS PYGB, CRH, CRY1 MAPT 968/4885MEN1 1037/4885KMT2A 3027/4885
US-12312599-B2 Methods, compositions, and kits for producing beige adipocytes and treating metabolic disorders FABP4, LIPC, PNLIP MAPT 3885/4885MEN1 3661/4885KMT2A 3537/4885
US-20260081034-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS CRH, HCRTR1, PER2 MAPT 1473/4885MEN1 2123/4885KMT2A 2802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.