Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736594 | 1.00 | KDM4E (0.36) | KDM4ENPSR1TOP1SLC16A1MEN1 | |
| SCHEMBL7739143 | 0.77 | NR1H2 (0.40) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7739139 | 0.77 | NR1H2 (0.40) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29138776 | 0.75 | MTNR1A (0.51) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7738442 | 0.71 | TACR1 (0.46) | KDM4ENPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7737554 | 0.70 | NR1H2 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7737549 | 0.70 | NR1H2 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7738387 | 0.70 | MEN1 (0.31) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7738394 | 0.70 | MEN1 (0.31) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7738441 | 0.69 | AKR1B1 (0.32) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |